1、The above methods are all based on image analysis. 上述方法都是基于圖像分析。
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2、 There are several traditional, non-image based methods for quantification of internal granule structure. 有幾種傳統的,非基于圖像的量化內部顆粒結構方法。
3、 These methods include pycnometry [27], mercury porosimetry [19,28,29], nitrogen adsorption technique or 這些方法包括pycnometry、汞porosimetry[27](19、28、29]、氮氣吸附技術或 BET analysis [28,30] and Inverse Gas Chromatography, IGC, [31]. BET分析[28,30]以及反氣相色譜儀,或IGC[31]。
4、 Acquiring the internal granule structure by modern methods, such as image-based techniques, is often costly due to operating and capital costs of equipment such as X-ray micro-tomography (XMT), Magnetic Resonance Imaging (MRI), and Transmission Electron Microscopy(TEM). 用現代的方法獲取內部顆粒結構,如影像學技術,往往是昂貴的,由于操作及資金成本，如x射線micro-tomography(XMT)、磁共振成像(MRI)和透射電子顯微鏡等設備(TEM)。
5、 However, these are more accurate and give more information which cannot otherwise be obtained by the traditional methods. 然而,這些都是更準確的，給出的信息更多, 這些信息也無法用傳統方法獲得的。
6、XMT has been used in the field of granulation technology for analysis of the internal structure of granules [19] and tablets [32], external particle shape [33] and characterisation of agglomerate structure for DEM XMT已被用于顆粒技術領域，分析顆粒(19]和片劑[32]的內在結構外部顆粒形狀,[33]和DEM的結塊性結構特征 simulations [14]. 模擬[14]。
7、 An important challenge of the granulation technology is to produce consistent granule structure and shape which in turn lead to more uniform properties such as strength and dissolution rate. 顆粒技術上的一個重要的挑戰是生產出結構和形狀一致的顆粒，從而得到更均勻的性質,如強度、溶解率。
8、 This is difficult without introducing a method to quantify the granulestructure. 如果沒有一個定量研究顆粒結構的方法，這將是非常困難的。
9、In this paper we use some structure descriptors such as chord length distribution and phase function to enable quantification of internal structure of granules. 在本文中,我們使用一些結構描述符,如弦長分布和相位函數, 從而量化顆粒的內部結構。
10、 The characterisation of granule strength [34–39] and structure [14] has previously been reported. 各種顆粒的強度[34-39]和結構的特征[14]過去曾有過報告。
11、 However, there is no work on the effect of different operating conditions, such as impeller speed on the internal granule structure. 然而,沒有關于不同的操作條件對工作的影響,如葉輪速度對內部顆粒結構的影響的報告。
12、 The objective of this work is to acquire the internal structure of granules by high resolution X-ray microtomography and to analyse it using a software package developed by Stepanek et al. [40]. 本文的目的是利用高分辨x射線microtomography獲得顆粒的內部結構，并使用一個由Stepanek 等人開發的軟件來分析它。
13、【40]。
14、 The granules used in this work were produced at three different impeller speeds in a high shear granulator. 這項工作使用的顆粒是在三種不同速度的葉輪高剪切造粒下產生的。
15、滿意請采納。
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